產(chǎn)品描述: | Tetrapeptide-30 是一種由四個(gè)氨基酸組成的亮膚肽,可充當(dāng)酪氨酸酶抑制劑,通過(guò)減少酪氨酸酶的數(shù)量以及抑制黑色素細(xì)胞激活而淡化色素沉著,均勻膚色。 |
體外研究: |
Tetrapeptide-30 (0-10 μg/mL, 24 h) can effectively reduce UVB-induced gene expression of IL-6, TNF-α and POMC (proopiomelanocorticotropin), and also decreased IL-8 gene expression in a dose-dependent manner. Tetrapeptide-30 (PKEK) is highly hydrophilic and has good skin penetration in microemulsion. |
參考文獻(xiàn): |
1. Alessandra Marini, et al. Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol. 2012 Feb;21(2):140-6.
2. Reinhard H H Neubert, et al. Dermal peptide delivery using enhancer moleculs and colloidal carrier systems. Part II: Tetrapeptide PKEK. Eur J Pharm Biopharm. 2018 Mar;124:28-33. |
保存條件: |
-20℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
1.998 ml |
9.988 ml |
19.976 ml |
5 mM |
0.4 ml |
1.998 ml |
3.995 ml |
10 mM |
0.2 ml |
0.999 ml |
1.998 ml |
50 mM |
0.04 ml |
0.2 ml |
0.4 ml |
|
注意: |
部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。 |