| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購買數(shù)量 |
|---|---|---|---|---|---|---|---|
| S81540-2mg | 98% | ￥424.00 | 5 | - | - | - |
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| S81540-5mg | 98% | ￥640.00 | 3 | - | - | - |
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| S81540-10mg | 98% | ￥1160.00 | 6 | - | - | - |
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| S81540-25mg | 98% | ￥2240.00 | 6 | - | - | - |
|
| S81540-50mg | 98% | ￥3520.00 | 貨期：2-3天 | - | - | - |
|
| S81540-100mg | 98% | ￥4960.00 | 貨期：2-3天 | - | - | - |
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Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.
| 產(chǎn)品描述： | Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | ERK1:98 nM (Kd);RasGAP:212 nM (Kd);RSK1:0.5 μM (IC50);RSK2:2.5 μM (IC50);RSK3:3.3 μM (IC50);RSK4:10 μM (IC50);ERK;?Raf;?S6Kinase | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Chen S, et al. Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71. 2. Mertins SD, et al. A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept. PLoS One. 2013;8(2):e57099. | ||||||||||||||||||||
| 溶解性： | DMSO : 25 mg/mL (45.41 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存條件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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