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Entecavir

    
98%

Entecavir

源葉(MedMol)
S83243 一鍵復(fù)制產(chǎn)品信息
142217-69-4
C12H15N5O3
277.283
恩替卡韋;9-(4-羥基-3-羥甲基-2-亞甲基環(huán)戊-1-基)鳥嘌呤;2-氨基-9-((1S,3R,4S)-4-羥基-3-(羥甲基)-2-甲烯基環(huán)戊基)-3H-嘌呤-6(9H)-酮;恩替卡韋-D2;Entecavir;Entecavir Baraclude;2-Amino-1,9-Dihydro-9-[(1S,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methyle
貨號 規(guī)格 價(jià)格 上海 北京 武漢 南京 購買數(shù)量
S83243-5mg 98% ￥410.00 6 - - -
S83243-10mg 98% ￥580.00 10 - - -
S83243-50mg 98% ￥1590.00 7 - - -
S83243-100mg 98% ￥2650.00 5 - - -
產(chǎn)品介紹 參考文獻(xiàn)(1篇) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.

產(chǎn)品描述： Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.
靶點(diǎn)： HBV
體內(nèi)研究： Daily oral treatment with BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months is effective in reducing the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks
細(xì)胞實(shí)驗(yàn)： BMS 200475 is prepared in phosphate-buffered saline (PBS) and diluted with appropriate medium containing 2% fetal bovine serum. HepG2 2.2.15 cells are plated at a density of 5×105 cells per well on 12-well Biocoat collagen-coated plates and are maintained in a confluent state for 2 to 3 days before being overlaid with 1 mL of medium spiked with BMS 200475. Quantification of HBV was performed on day 10
參考文獻(xiàn)： 1. Xie B, Sun D, Du Y, et al. A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts[J]. Cell research. 2019: 1. 2. Sham, H., Kempf, D., Molla, A., Marsh, K., Kumar, G., & Chen, C. et al. (1998). ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease. Antimicrobial Agents And Chemotherapy, 42(12), 3218-3224. doi: 10.1128/aac.42.12.3218
溶解性： Soluble  in  DMSO
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 3.606 ml 18.032 ml 36.064 ml
5 mM 0.721 ml 3.606 ml 7.213 ml
10 mM 0.361 ml 1.803 ml 3.606 ml
50 mM 0.072 ml 0.361 ml 0.721 ml
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質(zhì)檢證書(COA)

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批號：JS298415 貨號：S20001-25g
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