產(chǎn)品介紹
NOS抑制劑;NOS inhibitor;產(chǎn)品介紹:在一項研究中已經(jīng)報道了氨基胍鹽酸鹽可作為動物一氧化氮(NO)-合酶的抑制劑。已采用傅立葉和最小二乘法對鹽酸氨基胍的晶體結(jié)構(gòu)進(jìn)行了研究。其晶體為單斜晶體,氨基胍離子的胍部分是平面結(jié)構(gòu)。產(chǎn)品用途:氨基胍鹽酸鹽可作為一氧化氮合酶(NOS)的抑制劑,用于研究其對大鼠結(jié)扎性牙周炎牙槽骨損失的影響。它可用于合成5-脒腙衍生物,其具有抗 大腸桿菌 和 金黃色葡萄球菌的抗菌活性。;Product IntroductionAminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.Product UsageAminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.